Xiaogang in a sudden car accident in the unfortunate on-the-spot coma, the “inner shell” was seriously injured, craniocerebral injury. Sent to the local hospital for treatment, cranial CT examination suggests subdural hematoma, cerebral contusion, brain hernia formation, due to the critical situation, the doctor did for her cerebral contusion removal and decompression of the flap, life can be preserved, postoperative recovery is also good, but left behind a skull defect, frontotemporal parieto-occipital part of the cranium of a large area of the skull is missing. The cranial defect caused the originally confident Xiaogang to suffer a huge blow, and the originally cheerful personality of Xiaogang was not willing to show his smile again, and he was always gloomy and low. Because of the skull damage, Xiao Gang’s brain and nerve functions were also affected. His eyesight dropped drastically, and his mouth and nose were crooked. He decided to cure his skull no matter what. Although the local hospital could repair the skull, the materials used to do so were very limited. So he came to our neurosurgery department for treatment. He came to our neurosurgery department to receive treatment because he learned that our hospital has very advanced materials for repairing the skull, which can enable him to return to a healthy life again. After Xiao Gang was admitted to the hospital, after a series of examination and evaluation, Professor Zhu of the Department of Neurosurgery arranged for the staff to collect Xiao Gang’s cranial CT data and customized a PEEK material repair plate for him based on this three-dimensional data. Soon after, Prof. Zhu performed the skull repair surgery for Xiaogang. After exposing the bone window during the surgery, the 3D prefabricated PEEK repair plate was inlaid into the bone window tightly to achieve precise anatomical repositioning. After the surgery, Xiao Gang’s skull shape was restored intact and effective mechanical protection of brain tissue was realized. At the same time, the neurological function gradually improved, and he regained his beautiful and natural appearance. This surgery has brought back Xiao Gang’s self-confidence and happiness.