If the heart is uncomfortable after drinking alcohol, you can apply drugs at home, you can take nitroglycerin, sublingual nitroglycerin, and observe the situation, usually because of drinking too much and lead to the constriction of the capillaries, which caused by the contraction of the aorta, usually because of the coronary artery of the heart blood supply is incomplete and lead to cardiac discomfort, through the nitroglycerin can be relieved to a certain extent. If the application of nitroglycerin is not relieved, you can also go to the hospital to inject antidepressants, such as injection of naloxone hydrochloride to relieve alcohol, if necessary, the application of Xinkang, nitroglycerin injection to relieve cardiac discomfort caused by drinking alcohol after the heart, or you can also drink antidepressants, such as drinking concentrated sugar water, concentrated honey water, or drinking concentrated green bean water, can play a role in promoting diuresis and relieve the cardiac discomfort.