”Migraine” is a relatively common disease, and people have experienced migraine at one time or another in their lives, but some patients do not pay attention to it because the pain level varies depending on the condition. The main manifestation of migraine is episodic moderate-to-severe, throbbing headache, and some patients may have nausea and vomiting. What are the causes of migraine in most patients? Most migraines occur due to the compression of nerves by blood vessels, and the pain is triggered by the release of pain-causing transmitters under certain conditions or stimuli. This kind of severe pain is often unbearable for patients, and some patients bang their heads against the wall during the pain to relieve it. If the pain is not treated in the long run, the patient’s condition will become more and more serious, making the patient feel inexplicably uneasy and affecting the patient’s health and normal life. Therefore, after getting migraine, treatment measures should be taken as soon as possible to avoid bringing more harm. Migraine treatment is divided into two stages. The first stage of treatment is for mild migraine, which mainly relies on medication to relieve pain, usually taking painkillers such as non-steroidal anti-inflammatory drugs and opioids, and idiosyncratic drugs such as ergot preparations and treprostin, which can only play a role in the patient’s pain and are basically ineffective for the treatment of migraine. The second stage of treatment is for moderate to severe migraine and relies mainly on surgical treatment to relieve the compression between the blood vessels and the nerves through manifest microvascular decompression, thus making the pain disappear.