Sleeping suddenly heart discomfort need to identify the cause, may be physiological, may also be pathological; physiological reasons need to adjust the lifestyle, pathologically caused by the need for targeted treatment under the guidance of the doctor, such as drug therapy, surgical treatment, and so on. 1. Physiological: Considering the discomfort in the precordial area caused by the compression of the chest cavity during sleep, or it may be the intake of a large amount of coffee and strong tea before going to bed, which stimulates the sympathetic nerves and leads to tachycardia, and makes the patient feel uncomfortable about his/her heart. By changing the sleeping position and avoiding coffee and strong tea before going to bed, the condition can be improved. 2. Pathologic: (1) Patients with coronary heart disease may experience symptoms such as chest tightness and shortness of breath, suffocation in the precordial area, and dyspnea during sleep. Commonly used drugs include nitrate drugs such as nitroglycerin, beta-blockers such as bisoprolol, and calcium channel blockers such as nifedipine; consider surgical coronary artery revascularization if necessary. (2) Symptoms of cardiac neurosis can occur before going to sleep, when trying to wake up and just waking up, manifesting as palpitations, precordial pain, shortness of breath, and so on. Commonly used drugs include sedatives such as diazepam, beta-blockers such as metoprolol, and autonomic regulators such as ghrelin. But do not rule out other factors caused by the symptoms are obvious, if the adjustment of lifestyle is not obvious, to go to the hospital in a timely manner to clarify the cause of the disease, follow the doctor’s instructions standardized treatment.