In general, there is still a chance of surgical cure for mid-stage cancer, so don’t give up the treatment, it is definitely salvageable. Of course, the treatment and prognosis of mid-stage cancer may be different for different sites. Generally speaking, mid-stage cancer may have peripheral lymph node metastasis, but no distant metastasis. If the cancer can be cured by surgery, it can be cured by surgery and then treated with adjuvant radiotherapy and chemotherapy. Adjuvant radiotherapy is more often done after surgery for mid-stage cancer because the postoperative pathology may reveal more metastatic lymph nodes. Some of them may not be able to do surgery at the beginning, but they can also consider preoperative neoadjuvant radiotherapy, which aims to shrink the primary tumor lesions and control the metastatic lesions, and also has the effect of reducing the stage. It can make some cancers that cannot be cured by surgery into cancers that can be cured by surgery, and it is important to look at the side treatment.