Liver coma is a critical illness in the decompensated phase of liver cirrhosis, and the complication can also occur in acute liver failure and hepatocellular carcinoma. Hepatic encephalopathy is a syndrome of neuropsychiatric abnormalities of varying severity based on metabolic disorders caused by acute or chronic liver dysfunction or various abnormalities of portal vein-body circulation shunts. The main manifestations of hepatic encephalopathy are neurological dysfunction, psycho-behavioral abnormalities, and even coma in severe cases. Hepatic encephalopathy used to be called hepatic coma, but the latter is only the more serious part of hepatic encephalopathy and does not represent the whole picture. The disease needs to be treated urgently in a comprehensive hospital setting, and this article focuses on the details and important things to pay attention to after hospital treatment for patients in hepatic coma, in the hope of reducing recurrence and improving the quality of life and survival time in the long term. Why liver coma occurs The liver is similar to a chemical plant in the human body. Patients with cirrhosis in the decompensated stage of the liver have a significant decrease in the liver’s ability to work, especially with protein-based substances, so eating more meat, eggs or even milk at this time can easily induce hepatic encephalopathy. In addition, the overloaded liver is particularly demanding on other body requirements, such as constipation, intestinal infections, lung infections, abdominal infections, gastrointestinal bleeding, etc. can induce hepatic encephalopathy, and even potassium and sodium deficiency may also induce hepatic encephalopathy. It can be seen that many factors can lead to hepatic encephalopathy, and chronic encephalopathy is also prone to recurrent attacks, so you can’t do without this knowledge. Early manifestations of hepatic coma Early manifestations of hepatic coma can be dizziness and nausea, which are more difficult to detect. Some patients can show that they cannot dress themselves, cannot find home or toilet, urinate or defecate anywhere, or behave abnormally, such as unable to count, irritable, boastful, or even attack others, etc. Family members who find abnormalities in patients need to pay attention and send them to hospital for treatment in time. Treatment of hepatic coma Doctors usually improve the patient’s condition by giving drugs to promote liver metabolism and correcting triggering factors, such as anti-infection, albumin supplementation, correction of electrolyte disorders and control of gastrointestinal bleeding. Key points to focus on for patients in hepatic coma Long-term application of drugs to promote liver metabolism, such as ornithine monophosphate, long-term application of lactulose to keep the bowels open, about three times a day is appropriate, appropriate application of diuretic drugs to maintain their urine volume and weight relatively stable, and cooperation with doctors to find a suitable recipe for themselves, both nutritious and to avoid inducing hepatic encephalopathy, part of the liver nutrients can be properly ingested. The rest is to try to avoid common infections such as colds and consumption of unclean food. In short, all this is aimed at minimizing the recurrence of hepatic encephalopathy and maintaining liver function in order to really improve the quality of life and survival time of patients.