If a patient’s diastolic blood pressure is still not maintained normal when taking antihypertensive drugs, in this case, it is possible that the patient’s antihypertensive drugs are not chosen correctly, or his blood pressure is relatively high and he simply takes only the same antihypertensive drugs without combination, which is relatively ineffective. For hypertensive patients with high diastolic blood pressure, the preferred antihypertensive drugs are welfare or sartan antihypertensive drugs, and the representative drugs are perindopril, benazepril, valsartan and coxsartan. If the diastolic blood pressure is not well controlled by taking any of the above antihypertensive drugs, it can also be combined with beta-blockers, and the representative drugs include metoprolol and bisoprolol. In addition, calcium channel blockers, such as amlodipine and felodipine, can be combined. If the diastolic blood pressure does not fall within the standard range after the patient has adjusted the medication regimen, it is important to consider whether it is because the patient is only taking medication but not combined with lifestyle interventions to improve it.