Sore throat usually cannot be treated with local painkiller injection. The symptom may be caused by dry throat, acute epiglottitis, laryngitis and other factors, which can be treated by general treatment, medication (e.g. penicillin sodium) and surgery. 1. Dry throat: usually drink more water to relieve the symptoms of dry throat and keep the humidity of the environment suitable. 2. Acute epiglottitis: when swallowing difficulty, can not eat can be through the vein to replenish the nutrients needed by the body, to keep the airway open, oxygen can be inhaled when lack of oxygen; can use amoxicillin, cefuroxime and other drugs for anti-infective treatment; the use of budesonide nebulization to relieve local swelling, aminobromine hydrochloride to dilute sputum; local abscess can be incised and drained; respiratory difficulties can be established to relieve the artificial airway. 3. Laryngitis: the disease will lead to sore throat, hoarseness and other symptoms, patients should pay attention to rest, avoid excessive use of voice. Acute laryngitis can use penicillin sodium, amoxicillin and other drugs to fight infection, and when the pain is severe, ibuprofen and acetaminophen can be used for treatment. Chronic reflux laryngitis can use omeprazole, pantoprazole and other drugs to relieve the symptoms of reflux. Laryngeal pain should be timely to the hospital, identify the cause of the disease after treatment, strictly comply with the doctor’s prescription medication.