The treatment of bilateral blepharospasm is still a challenge for the medical community, because the true cause of bilateral blepharospasm and the pathogenesis of the disease are still unclear, and most scholars currently believe that it is a dysfunction of the central nervous system of unknown origin. Therefore, many treatments are symptomatic rather than cause-specific, making it difficult to obtain a cure. This is the preferred treatment for blepharospasm, and commonly used drugs include clonidine, haloperidol, thiopiridol, benzhexol, etc. Some patients will have some effect at the beginning of the disease, but the effect will gradually diminish as the disease progresses, or they may stop taking the drugs because they cannot tolerate the side effects; 2. Botox is the most effective treatment for eyelid spasms. It is injected into the upper and lower eyelids to reduce the degree of spasm, and the effect is obvious after the injection. The biggest problem with Botox is that some people are allergic to Botox, cannot accept the side effects of Botox, or the efficacy of Botox is not obvious, so the use of Botox injections is limited. Surgical procedures for the facial nerve, which attempt to attenuate the markedly hyperactive downward nerve conduction, can be observed in some patients with good results, but not all patients can benefit from surgery, so current surgical treatment is only a complementary treatment option for patients for whom medication and botulinum toxin therapy have failed, and needs to be chosen carefully.