1, drug therapy: According to the pathogenesis of MGD, drug therapy can be divided into the following categories: 1, antibiotics: blepharitis and MGD are inseparable and have a mutually reinforcing effect, so anti-infective drugs have long been essential. The topical ocular medications for MGD are erythromycin, bacitracin, trimethoprim, polymyxin and other eye drops, but they are not effective for severe blepharitis and MGD. In severe cases, oral antibiotics can be used, usually tetracyclines such as tetracycline, doxycycline, and minocycline.2. Androgen therapy: For patients with abnormal sex hormone levels, androgens can improve the structure of the lid gland, regulate the function of the lid gland, and improve the quality of the lipid layer.3. Immunomodulation: Glucocorticoids and 0.05% cyclosporine A drops have been tried to treat inflammatory MGD and refractory MGD. 4.Nutritional support therapy: Recently, some people have tried to apply artificial tears containing lipids such as phospholipids, saturated and unsaturated fatty acids and triglycerides to treat MGD patients with satisfactory results. Oral administration of linoleic acid and linoleic acid essential fatty acids may improve symptoms in patients with chronic blepharitis.5. N2-Acetylcysteine therapy: A mucolytic agent used to treat chronic bronchitis and pulmonary disorders, it can be taken orally to treat blepharitis. Of course, some patients with mild to moderate MGD may not be able to adhere to treatment in the face of the side effects, compliance and cost of long-term medication. 2. Eyelid hygiene care: This has become one of the main methods of treatment for MGD recently. The use of isotonic warm sodium chloride solution to wet compress the eye and wipe the eyelash root near the lid gland to remove waxes that are not conducive to lipid dispersion, along with preservative-free artificial tears, can provide relief and prolong tear film rupture in most patients. The use of baby shampoo for eyelid hygiene has also been suggested, but it is not widely used in clinical practice because of its saponification effect (leading to lipid solidification and deposition) and because it is not approved for topical use in the eye. 3. Physical therapy: The melting point of the lipid mixture of the lid glands varies between types of lids, and chronic blepharitis raises the melting point of the lipids secreted by the lid glands. Hot compresses on the eyelids can help increase local blood flow to the eyelids, melt the lipids of the lid glands, and contribute to the stability and uniformity of the lipid layer of the tear film, which can relieve irritation in patients with MGD (especially in contact lens users). The most commonly used method is a warm towel on the eyelid. Commercially available eye heaters include the IWCD (Eye Hot, Cept, Tokyo) and the disposable eye warmer (Eye Warmer, Kao, Tokyo). In conclusion, there is no unified international standard for the diagnosis and classification of MGD; the factors that cause MGD are diverse and complex, making it difficult to prescribe the right medication; even treatment takes a long time to be effective and requires long-term follow-up care, and there is no substantial means to eradicate blepharospasm. However, as the quality of life improves, MGD will receive more and more attention from scholars.