Acne and chloasma are common clinical skin diseases in women. Acne is associated with wind-heat in the lung, heat in the spleen and stomach, and heat in the internal organs. There are deficiencies and realities in chloasma. The deficiencies are blamed on the deficiency of liver and kidney yin and the dysregulation of the flush, while the real ones are mostly related to the damp-heat in the lower jiao, so they are treated by tonifying the liver and kidney, regulating the flush and clearing the damp-heat. In clinical cases, acne and chloasma coexist. In the 20s and 30s, it is more common to see wind-heat in the lung and damp-heat in the internal organs, while in the 40s and 50s, it is more common to see liver-kidney yin deficiency, dysregulation of the flush and damp-heat in the lower jiao. Modern medicine believes that the causes of acne are not only related to endocrine metabolic factors, but also to excessive sebum secretion, hyperkeratosis of hair follicles, and bacterial infections in hair follicles, etc. The combination of white flowering snake’s tongue herb, raw hawthorn, bitter tea, and tea tree root with Salvia miltiorrhiza, yellow essence, and radix et al. can not only reduce facial oil secretion, but also reduce inflammatory infections in hair follicles. Chronic inflammation of the pelvic reproductive system in female patients is also the cause of dysregulation of the flush and damp heat on the face, causing discoloration, so attention should be paid to the use of scutellaria baicalensis, cypress, deer artichoke, summer cress to clear heat and remove dampness, white fruit, gorgonian, dragon bone and other astringent products.