Post-stroke shoulder-hand syndrome is a condition in which patients present with pain in the scapular girdle and hand joints of the affected upper extremity after cerebral hemorrhage or cerebral infarction, with restricted movement and vasomotor changes, and significant skin and muscle atrophy in the late stage. It is mostly seen within 3 months after the disease (80%), especially in 2-16 weeks after the disease, and in a few cases in 4-7 months. 1. The pathogenesis is unknown. It is thought to be related to the abnormal function of the autonomic nervous system, closely related to the mesencephalon and frontal, parietal, temporal and limbic cortical lesions, and the lack of warmth and insufficient exercise of the paralyzed limbs are also important causes. Doctors should be alert and instruct patients to prevent its occurrence. Guo Xiaoshuang 2. Clinical manifestations (1) The first symptom is mostly pain and limitation of movement around the shoulder on the hemiplegic side, with significant limitation of lifting, abduction and external rotation of the affected upper limb, and severe pain caused by passive activities, quite similar to periarthritis of the shoulder. (2) Subsequently, the dorsum of the hand and fingers are swollen, the skin is red and cyanotic, occasionally pale, the skin temperature is high, the fingers are in extension, flexion is limited, and passive activity may cause severe pain. (3) In the advanced stage, the skin and muscles of the hand and peri-shoulder gradually atrophy and the joints contract. 3.Differentiation between this disease and frozen shoulder Frozen shoulder only causes pain and limited activity around the shoulder, limited lifting, abduction and external rotation of the affected limb, but not limited wrist and finger activity and pain, hand swelling, skin color and skin temperature change, hand muscle atrophy, etc. 4.Treatment The key is early diagnosis and treatment. (1) Prednisolone acetate: local injection of biceps tendon and infraspinatus tendon once a week; also local injection of prednisolone, vitamin B12 and tramadol combination. (2) 2% nufcaine for stellate ganglion closure on the affected side. (3) 2％ nufcaine 25ml plus 5% glucose solution 500ml, 1 time/day, a course of treatment for 10d. (4) Massage, physiotherapy and body therapy can be applied.