Knee pain when going up the stairs is common in knee osteoarthritis, synovitis, chondromalacia patella, etc., according to the patient’s condition to take the appropriate treatment, including general treatment, physical therapy, drug treatment and surgical treatment. 1. Osteoarthritis of the knee: belongs to the degenerative changes of the knee joint, need to pay attention to reduce strenuous exercise and weight-bearing activities; can be given local hot compresses to relieve joint pain; can be given to ibuprofen and other non-steroidal anti-inflammatory drugs, such as the treatment of the joint cavity injection of sodium hyaluronate and other treatments when necessary. In severe cases, surgical treatment can be given, such as knee arthroplasty. 2. Synovitis: especially chronic knee synovitis, there may be pain when going up the stairs. You need to pay attention to rest, reduce knee activities, oral or topical diclofenac sodium and other non-steroidal anti-inflammatory drugs, but also intra-articular injection of trimethoprim and other glucocorticoid drugs treatment. If conservative treatment is ineffective, arthroscopic debridement can be performed. 3. Chondromalacia patella: Conservative treatment can also use ibuprofen and other painkillers, joint cavity injection of sodium vitrate, etc. Conservative treatment is ineffective, can be given to the limited chondroplasty and drilling, lateral support band laxity surgery. It is recommended that the patient go to the hospital, complete the auxiliary examination, in order to clarify the cause of the disease, and then give the appropriate treatment by a professional doctor, and the drugs need to be used under the guidance of a professional doctor.