1.HsCRP Origin When it comes to hypersensitive C-reactive protein (hsCRP), we need to know about C-reactive protein (CRP). hsCRP is an acute temporal protein synthesized during inflammation or injury, which is involved in a variety of physiological and pathological processes in the body. hsCRP can sensitively reflect the presence of inflammatory response in the body, and play both anti-inflammatory and pro-inflammatory roles. Ultrasensitive C-reactive protein (hsCRP) is the same kind of protein as common CRP, but it is named because of its more sensitive measurement method. 2. hsCRP is an important inflammatory marker In recent years, with the study of the etiology and pathogenesis of cardiovascular events, chronic inflammation has been found to play an important role in their formation and development. Inflammation plays a key role in the pathophysiology of atherosclerosis, and atherosclerosis as the pathological basis of coronary heart disease is a chronic inflammatory disease. It has been found that inflammatory response is an important influence on arterial structure and function, and various inflammatory responses have an important link with arterial elastic function. Ultrasensitive C-reactive protein (hsCRP) is an important inflammatory marker. 3. hsCRP is a predictor of cardiovascular disease Studies have confirmed that elevated hypersensitivity C-reactive protein (hsCRP) is associated with increased risk of adverse cardiovascular outcomes. 2003 the American College of Cardiology and the Centers for Disease Control developed new criteria for determining the risk of cardiovascular disease, namely, hs-CRP <1mg/L is low risk, 1-3mg/L is moderate hs-CRP <1mg/L is considered low risk, 1-3mg/L is considered moderate risk, and 3mg/L or more is considered high risk. Studies have shown that hs-CRP ≥2.0 mg/L is a valid predictor for the development of cardiovascular disease in the Chinese population. Also, clinical studies found that plasma hs-CRP levels were significantly higher in patients with coronary artery disease than in those without coronary artery disease, and among patients with coronary artery disease, plasma hs-CRP levels were significantly higher in those who had had a myocardial infarction than in those who had never had a myocardial infarction. As with cardiovascular disease, serum hs-CRP is also a predictor of cerebrovascular events. Epidemiological surveys have shown that people with elevated hs-CRP levels are two times more likely to have an acute stroke and three times more likely to have a myocardial infarction than normal healthy people. 4, drugs to reduce serum hsCRP level hs-CRP is not only a predictor of cardiovascular accidents, but also one of the indicators of prognosis and evaluation of the efficacy of treatment. So how to reduce the level of hs-CRP in the serum? (1) Statins can significantly reduce the level of serum hs-CRP, and statin therapy before percutaneous coronary intervention can reduce mortality and prolong survival. (2) Thiazolidinediones, antidiabetic drugs, can reduce hs-CRP levels while improving insulin resistance. (3) Anti-platelet agents, which can help reduce serum hs-CRP levels and also reduce body weight.