The hypothalamus is one of the components of the mesencephalon, also known as the hypothalamus, and is very small, accounting for about 0.3% of the weight of the whole brain. Hypothalamic damage is mainly manifested as 6 major symptoms: 1, central uremia, mostly manifested as polyuria, polyhydramnios, thirst, lower urine specific gravity, etc. 2, thermoregulation disorders, can be manifested as central hyperthermia and intolerance of high temperature environment, can also be manifested as hypothermia. 3, feeding abnormalities, can be manifested as hyperphagia, a large increase in food consumption leading to excessive obesity, called hypothalamic obesity, can also lead to appetite loss, anorexia, wasting, etc. 4, sleep disorders, can be manifested as insomnia, anorexia, wasting, etc. 4, sleep disorders, can be manifested as insomnia, anorexia, etc. 4.Sleep disorders, can be manifested as insomnia, can also be manifested as excessive sleep or drowsiness. 5.Disorders of reproductive and sexual function, can be manifested as precocious puberty, mental retardation, can also be manifested as obesity reproductive incompetence. 6.Autonomic dysfunction, can be manifested as blood pressure instability, heart rate changes, etc.