What are the effects and side effects of aminophylline?

Aminophylline its main action is to have a direct relaxation effect on the smooth muscle of the respiratory tract. Clinically, it can be used in the treatment of bronchial asthma, wheezing bronchitis, obstructive emphysema and other relief of wheezing symptoms, but also can be used in asthma caused by cardiogenic pulmonary edema. The main component of aminophylline is theophylline and ethylenediamine complex salt, and its pharmacological effect mainly comes from theophylline. Aminophylline can act directly on the respiratory tract smooth muscle, so that the respiratory tract smooth muscle relaxation, in addition to enhance the diaphragm contraction ability. In addition to asthma, it relaxes the smooth muscle of the biliary tract, dilates the coronary arteries and has mild diuretic, cardiotonic and central excitatory effects. Aminophylline side effects may include nausea, vomiting, headache, and agitation. If injected intravenously or titrated in too large a volume, too high a concentration, or at too fast a rate, it can cause dizziness, palpitations, arrhythmia, and even serious reactions such as sudden drop in blood pressure, delirium, muscle tremors, or convulsions. This drug is contraindicated if you are allergic to aminophylline, have an active peptic ulcer, or have uncontrolled convulsive disorders. If you need to use aminophylline, it is recommended to regulate its use under the guidance of a doctor to avoid delays or adverse reactions.