The methods of lowering blood sugar include the following: first, controlling diet; second, strengthening physical exercise; third, taking oral hypoglycemic drugs, oral drugs include pro-insulin secretagogues, which are commonly used for people with better pancreatic islet function. The most common drugs are sulfonylureas and non-sulfonylureas. The sulfonylureas include glimepiride, glipizide, and gliclazide, and the adverse effect is that they tend to cause hypoglycemia. Non-sulfonylurea insulin stimulating agents include nateglinide and repaglinide. The common class of biguanides is metformin, which is commonly used in patients with initial diagnosis of diabetes. α-Alglucosidase inhibitors, commonly used drugs are acarbose and voglibose, are mainly used to control post-prandial hyperglycemia mainly in diabetic patients, but adverse reactions of digestive tract, such as bloating, diarrhea, etc. can occur. Thiazolidinediones include pioglitazone, which is an insulin sensitizer that increases the sensitivity of cells to insulin. Enterostatin-related drugs include liraglutide and selegiline, which are the latest researched drugs with better glucose-lowering effect but higher cost. Fourth, subcutaneous injection using insulin is commonly used for patients with higher blood sugar and poorer pancreatic islet function. These are several methods to lower blood sugar.