Melasma on the back of the hands is related to many factors, such as pigmentation in the skin caused by emotions or sun exposure. The treatment of melasma on the back of the hand is the same as that of facial melasma, we should pay attention to sun protection and try not to directly expose the back of the hand to the sun when we go out, we can apply hydroquinone cream or azelaic acid cream twice a day, we need to insist on the treatment for three months to six months, we can take high dose of vitamin C and glutathione tablets orally for one to two months. You can also take oral Chinese medicine to regulate the treatment. If the chloasma on the back of the hand is more stable and there is no obvious change within one year, you can go to the dermatology department of the hospital for laser treatment.