Headaches, insomnia, teenage acne, women’s dysmenorrhea, menopausal syndrome, hand sweating, allergic rhinitis and other common clinical conditions often plague the majority of patients. Let’s start with a case. Ms. Liu, 36 years old, had persistent insomnia for 6 years. The patient complained of difficulty in sleeping, dreamy, easy to wake up, less than 3h of sleep a night, drowsy mind, long-term drug treatment is not effective. After two sessions of treatment, the patient felt easier to fall asleep and less dreaming, and the treatment was consolidated for one session. After one course of consolidation treatment, the insomnia was completely cured, and there was no recurrence in the follow-up period of one year. With the increasing pressure of work and competition in society, there are few patients with insomnia like Ms. Liu, and after a lot of repeated treatments and observations by pain doctors, stellate ganglion block plays a great role in improving the sleep quality of patients. Liu Qing, Department of Anesthesiology, Affiliated Hospital of Traditional Chinese Medicine, Luzhou Medical College Stellate ganglion block is not only a treatment for stubborn insomnia, but also a new scientific treatment method with positive efficacy, little side effects, and easy to implement, which can solve many common discomforts and diseases in people’s daily life, such as headache, insomnia, teenage acne, women’s dysmenorrhea, menopausal syndrome, hand sweating, allergic rhinitis, etc. Its indications are It covers a wide range of disorders, including cephalomaxillofacial disorders, upper limb and chest wall disorders, complex regional pain syndromes, and cardiopulmonary disorders. Why does stellate ganglion block therapy have such a broad scope of action? Let’s first understand what is a stellate ganglion and its block therapy. The stellate ganglion is a fusion of the 6th and 7th cervical ganglia and the 1st thoracic ganglion, sometimes including the 2nd thoracic ganglion and the middle cervical ganglion, and its postganglionic fibers are widely distributed in the skin area of the C3 to T12 segment, which is a sympathetic ganglion in function. Stellate ganglion block (SGB) is a minimally invasive treatment that involves the injection of local anesthetic into the loose connective tissue containing the stellate ganglion to block the sympathetic nerves innervating the head, face, neck, upper extremities and upper chest. Studies have shown that repeated stellate ganglion blocks are a revitalizing exercise for the vegetative nerves. Stellate ganglion block only inhibits the increased sympathetic activity and restores the sympathetic-vagal balance. It has little effect on normal sympathetic nerve activity. The nervous system is closely linked to the endocrine system, and the degree of sympathetic tension affects the secretion of many endocrine glands…. Clinical observations confirm that stellate ganglion block with lidocaine can improve sleep and treat insomnia. Stellate ganglion block significantly reduced the levels of cortisol, aldosterone, angiotensin II, 5-HT, and substance P in the blood of patients with pain. It is easy to see that stellate ganglion block can regulate the abnormal changes in the endocrine system. Stellate ganglion blockade can improve the abnormal blood rheological indexes. It was found that vasodilatation can occur about 5 min after stellate ganglion blockade, and blood flow increases by 75% after 15 min and continues for 70 min, and blood flow velocity increases by 58% after 15 min and continues for 60 min, and blood vessel diameter increases by 7%. This has been shown to be effective in the treatment of cerebrovascular embolism, angina pectoris, heart attack, and Raynaud’s disease. In addition, stellate ganglion blockade plays a crucial role in the body’s defense and in the stabilization and regulation of its own internal environment. Here are two more examples of the specific therapeutic mechanisms and effects of stellate ganglia. Stellate ganglion blockade can effectively increase the T-cell ratio in the T-cell/B-cell ratio and improve the activity of natural killer cells, inhibit the propagation of Propionibacterium acnes in patients with acne vulgaris, and help control infection. metabolism, promoting the recovery of lesions in patients with usual acne, and preventing the entry of acne contents into the dermis through tiny fissures causing perifolliculitis and the formation of inflammatory papules or pustules. Meanwhile, the addition of a small amount of dexamethasone injection to SGB medication can reduce post-treatment pain at the puncture site, promote the repair of facial damage and reduce its inflammatory response. Primary dysmenorrhea is commonly seen in young women. Most of the disease is related to plant nerve dysfunction and spasmodic contraction of the uterus, and some of them can be caused by dysplasia of the uterus, stenosis of the cervix and hyperflexion of the uterus, which affect the smooth flow of menstrual blood. The synthesis and release of prostaglandins from the uterus is an important cause of primary dysmenorrhea. The prostaglandin content in the endometrium and menstrual blood is significantly higher in dysmenorrhea than in normal women, and the higher the concentration of prostaglandins in the endometrium, the more severe the dysmenorrhea. It has been found that the amount of prostaglandins released from peripheral nerves increases after sympathetic excitation. The SGB method can inhibit sympathetic tension, maintain the stability of the hypothalamic neurological environment, regulate phytoconstriction, endocrine function and immune function, and inhibit the production of inflammatory mediators such as prostaglandins. The effect is to block, regulate and improve this abnormal pain and pathological process, and then promote its recovery. With the development and growth of pain clinics and wards, the concept of pain treatment has gradually gained popularity, and patients no longer have to endure the pain caused by neuroendocrine disorders, and the stellate ganglion block has brought a blessing to many subnormal patients, giving hope to some patients who have no access to medical care and whose treatment has been ineffective. Moreover, it is a scientific treatment method that is less invasive, more effective and economical, and has the significance and value of universal promotion. We expect and hope that in the near future, stellate ganglion therapy will be able to solve the problems caused by the above-mentioned diseases for more patients.