The treatment of atrophic gastritis mainly includes two kinds of treatments, namely, general treatment and drug treatment. 1. General treatment, more rest, pay attention to keep warm. Dietary attention should be paid to eating small meals, avoiding too rough, spicy and overheated food, chewing and swallowing slowly, and eating less salted and smoked food. 2. Medication (1) Eradication of Helicobacter pylori medicine, Helicobacter pylori positive to take the quadruple therapy treatment, the drugs are mainly omeprazole, clarithromycin, amoxicillin, pectin bismuth and so on. (2) Drugs to protect the gastric mucosa, suitable for gastric mucosal bleeding, erosion is more serious, such as aluminum sulfate and bismuth pectin. (3) Acid-suppressing or antacid agents, such as cimetidine, lansoprazole, etc. These drugs can reduce the secretion of gastric acid and relieve the symptoms of acid reflux and heartburn. (4) Gastrointestinal stimulants, such as domperidone, mosapride, etc. These drugs can promote gastric motility, which can relieve symptoms such as epigastric bloating and early satiety. (5) Other, poor sleep, excessive anxiety can be appropriate oral eszopiclone, amitriptyline and so on. The above drugs should be taken orally under the guidance of a doctor. Most patients have a better prognosis after reasonable treatment, but those who are accompanied by atypical hyperplasia of moderate degree or above should be examined by endoscopy regularly during the treatment period, so as to prevent the possibility of cancerous changes.