High TSH in pregnancy thyroid function five should be given medication under the supervision of a physician and controlled in a safe range. When the test for TSH (thyrotropin stimulating hormone) level is high after pregnancy, it indicates combined hypothyroidism. Since hypothyroidism increases the risk of preeclampsia, fetal miscarriage, malformations, and congenital defects, levothyroxine should be given under the supervision of a physician for active treatment in order to control the TSH in a safe range, and it can reduce the occurrence of adverse perinatal outcomes. Pregnant women with combined hypothyroidism should strengthen the nutritional guidance during pregnancy, closely monitor the intrauterine development of the fetus, and strengthen the fetal monitoring during pregnancy and delivery to be able to detect fetal distress and terminate the pregnancy in time to ensure the safety of mothers and infants. Thyroid function should be checked after birth to screen for neonatal hypothyroidism and provide timely intervention.