Ovarian plasmacytoid adenocarcinoma is a malignant tumor occurring in ovary, which may present with symptoms such as abdominal mass and abdominal pain, etc. After active treatment, patients can help to improve the prognosis and survival life. Ovarian plasmacytoid adenocarcinoma is a more common epithelial tumor in women, which is poorly differentiated and highly malignant. At present, the etiology of ovarian plasmacytoid adenocarcinoma is not clear. The clinical manifestations of patients with ovarian plasmacytoid adenocarcinoma are mostly nonspecific. Some patients may not have any uncomfortable symptoms, while some may have symptoms such as increased vaginal discharge, pelvic mass and abdominal pain. If the disease progresses, patients may have symptoms such as abdominal pain, masses, etc., which gradually worsen, and even distant metastasis and ascites may occur in the later stage. Once diagnosed with ovarian plasma adenocarcinoma, patients can take surgical treatment, such as comprehensive staging surgery, tumor cytoreductive surgery, which can be combined with chemotherapy, radiotherapy and other integrated treatments. At the same time, patients need to develop good living habits, have balanced diet, quit smoking and drinking, and can have appropriate physical exercise to strengthen the resistance of the body. Ensure sufficient rest time and do not overwork. Since ovarian plasmacytoid adenocarcinoma has a certain chance of recurrence, patients should follow the doctor’s instructions to have regular checkups during the treatment period, and consult the doctor in time if any abnormality occurs in the body.