Crohn’s disease and intestinal tuberculosis have certain differences in terms of etiology, clinical manifestations and treatment. 1. Etiology: intestinal tuberculosis is caused by tuberculosis bacillus infection of the intestinal tract; Crohn’s disease is a kind of chronic non-specific inflammatory disease of the digestive tract caused by a combination of factors such as environment, heredity, infection, immunity, etc. The etiology is not yet completely clear, and is considered to be environmental, genetic, infection, immunity and other factors. 2. Clinical manifestations: in addition to abdominal pain, diarrhea or constipation, abdominal masses and other gastrointestinal symptoms, tuberculosis may also have low afternoon fever, night sweats (sweating abnormally after going to sleep, and waking up sweating stops), fatigue and other symptoms of tuberculosis toxemia; Crohn’s disease will have abdominal pain, diarrhea, fever, malnutrition and other symptoms. 3. Treatment: intestinal tuberculosis is mainly treated against tuberculosis divergent bacilli, and can be treated with anti-tuberculosis drugs such as isoniazid and rifampicin; Crohn’s disease can be treated with aminosalicylic acid preparations such as mesalazine and salicylazosulfapyridine, and glucocorticosteroids such as budesonide can be used to control Crohn’s disease in the active stage. Patients with symptoms related to Crohn’s disease or intestinal tuberculosis are advised to visit a hospital.