The standardized medical name for Guillain-Barré syndrome is Guillain-Barré syndrome, and its onset is not generally associated with swimming. However, swimming can lead to overexertion and exposure to cold, which can induce colds and diarrhea and increase the likelihood of the onset of the disease, but this is very unlikely. Guillain-Barré syndrome is an acute autoimmune disease caused by infection or other causes. The main manifestations are weakness and numbness and tingling sensations in the extremities, which can spread to the whole body within 2 weeks, with generalized paralysis and labored breathing. The etiology of the disease is unclear and may be related to Campylobacter jejuni infection, viral infection, immunocompromise, surgery, trauma, and vaccination. Usually the sport of swimming does not involve any of these conditions and therefore does not directly cause Guillain-Barré syndrome. However, swimming can lead to excessive fatigue, exposure to cold, which can cause a decrease in resistance, viral infections, or swimming in unclean water, which can cause Campylobacter jejuni infections and diarrhea, then there is a possibility of indirectly inducing an autoimmune response that can cause Guillain-Barré syndrome. However, this probability is very small and is not a common clinical condition. If symptoms such as limb weakness, numbness and tingling occur after swimming, it is recommended to consult a doctor in time for a clear diagnosis and standardized treatment. Swimming exercise to avoid overwork, cold, pay attention to water quality clean, to avoid causing a variety of diseases.