Whether non-solid ground-glass nodules are benign or malignant can only be judged according to pathological examination, imaging examination and clinical symptoms, with pathological examination as the gold standard. 1. Pathological examination: for people with pleural effusion, the fluid can be aspirated for pathological smear examination to clarify whether there are cancer cells; clinically, considering that the possibility of malignancy is high, it is necessary to carry out pathological puncture biopsy in a timely manner, so as to clarify the benignness or malignancy of the nodule directly. 2. Imaging examination: if the edges of the nodules are smooth and the boundaries are clear under the CT examination of lungs, and if there is no change in the size and character of the nodules for a long period of time after regular review, benign nodules should be considered. If the CT examination of chest suggests that the boundary of the nodule is unclear, with burrs, lobes, vascular signs, pulling the surrounding pleura, or the diameter of the nodule is increasing during the review period, and the above signs appear, malignancy may be considered. 3. Clinical symptoms: If there are symptoms such as cough, sputum, fever, chest pain, pleural effusion, etc., and no obvious improvement in symptoms with anti-infection or anti-tuberculosis treatment, gradual emaciation and hemoptysis, combined with the above imaging examination, the malignancy of non-solid ground-glass nodule should be suspected to be high. If non-solid ground-glass nodules can be seen in the imaging examination, the patient should go to the hospital in time to clarify the cause of the disease and follow the doctor’s instructions for treatment.