LDL is abnormal if it is 4.27 mmol/L, a condition that is relatively high. For LDL cholesterol, if it is <2.6 mmol/L, it is a more desirable level; and the appropriate level is LDL cholesterol <3.4 mmol/L; if LDL cholesterol is between 3.4-4.09 mmol/L, it is borderline elevated; and when LDL cholesterol is ≥4.1 mmol/L, it is called elevated. This stratification criteria is based on the ninth edition, the latest internal medicine stratification, so if a patient has an LDL of 4.27 mmol/L, aggressive intervention therapy should be given. Because LDL is a risk factor for atherogenesis, it must be reasonably controlled within the standard range, and even patients with cardiovascular disease need to control it below the standard range to better prevent the progression of atherosclerosis.