Cerebral infarction is a disease caused by acute occlusion of cerebral blood vessels, which changes very rapidly after the onset and often leads to life-threatening in severe cases. The brain is the command center for human thinking and breathing and heartbeat; therefore, signs of near death are usually manifested in coma and changes in breathing and heartbeat. Coma: A relatively extensive and critical area of brain infarction can affect the centers that control arousal and respiratory circulation, resulting in various degrees of coma and changes in respiration and heartbeat. First of all, various kinds of coma appear, the degree of coma gradually increases, and the patient loses response to various strong stimuli, indicating that the degree of coma is very serious, and if there is also eye fixation and dilated pupils, it indicates that the condition is very serious and can be life-threatening. Respiration and heartbeat changes: Respiration and heartbeat are the basis of life support, and the brain is the command center of respiration and heartbeat. Brain herniation or brainstem infarction will destroy the respiratory and circulatory center, causing changes in the rhythm of respiration and heartbeat or even causing respiration and heartbeat to stop, which directly leads to death. The patient’s breathing will be severely irregular, with sighing or sobbing breathing, or nodding breathing, or even prolonged respiratory arrest, and the respiratory rate will drop significantly; the heartbeat will also change significantly, the heartbeat will lose its inherent rhythm, the blood pressure will drop significantly, and in severe cases, medication will be needed to maintain the blood pressure and heartbeat, the pulse will be shallow and fast and the blood pressure will drop, or the heart rate will drop or even suddenly stop, which are all serious changes in the condition, which can be life-threatening at any time. Therefore, when a patient with cerebral infarction appears coma with obvious changes in respiration and heartbeat, a sharp drop in blood pressure and other unstable vital signs, it is a signal that life safety is seriously threatened.