What are the causes of azoospermia? For men, there is sperm in order to have the right to have children, and the appearance of azoospermia causes great difficulties for male fertility. Azoospermia is mainly caused by testicular sperm production dysfunction, so what exactly is the cause of azoospermia? The following is an introduction to this problem. Azoospermia is a condition in which the sperm density is equal to 0. Even if the semen is centrifuged and examined, no sperm can be found. Clinically, azoospermia is usually diagnosed after 3 centrifugal microscopic examinations of the semen and after exclusion of non-ejaculation and retrograde ejaculation. What are the causes of azoospermia? (a) Obstructive azoospermia 1. congenital malformation, common symptoms include ectopic epididymal head, atresia of epididymal duct, absence or non-development of vas deferens; 2. infection, gonococcus, tuberculosis and some other bacterial infections, these factors can cause obstruction of epididymis and vas deferens; 3. cyst at epididymis compressing epididymal duct causing obstruction. (2) Sperm production disorders 1. congenital testicular abnormalities: abnormal testicular development or testicular location can cause sperm production disorders; 2. endocrine diseases, hyper or hypopituitarism, pituitary tumors, hyper or hypo adrenal function, hyper or hypothyroidism, these conditions can affect sperm production and cause azoospermia; 3. hereditary diseases: autosomal or sex chromosome abnormalities affect testicular sperm production. The expert in male infertility said, as long as reasonable and effective treatment, azoospermia patients families still have hope to carry their “baby”. The actual fact is that you should not be blinded, but you must go to a professional hospital to find out the cause before treatment, and then a professional expert will develop a suitable treatment plan for you.