Some experts state, “Azoospermia patients can only have children if they have IVF or give up on the treatment.” Is this really the case? The answer is of course no, no! The truth is: there are still many chances, and there is still a lot of hope! Azoospermia belongs to the common type of male infertility disease, according to epidemiological survey, the prevalence of normal male population is close to 1-2%, that is to say, 100 men, there are 1-2 people are azoospermia, of which 20% belongs to the obstructive azoospermia, 80% of the non-obstructive azoospermia. In obstructive azoospermia, epididymal obstruction accounts for 30-67%, which can be surgically recanalized through microscopic vasovaso-epididymal anastomosis, with a success rate of up to 80%; vas deferens medical obstruction accounts for 2-6%, which can be surgically recanalized through microscopic vasovaso-epidymal anastomosis, with a success rate of 75-99%. Comprehensive data on obstructive azoospermia, microscopic anastomosis may lead to the reopening of the spermatic duct in nearly 70% of patients! In non-obstructive azoospermia, when combined with varicocele, if microscopic spermatozoa ligation is performed first, nearly 40% of the patients can have sperms in the semen 1 year after the operation, and 60% of these patients can conceive naturally, and the remaining 60% of the patients can get sperms through microscopic testicular sperm retrieval for the treatment of ICSI or IVF; if there is no combination of varicocele, microscopic testicular If not combined with varicocele, microscopic testicular sperm retrieval can help 60% of patients to get sperm, of which 40% can get fertility through ICSI or IVF. Overall, for the treatment of difficult azoospermia patients, microscopic surgery can ultimately help 2/3 of the patients, so for azoospermia patients, should be familiar with microsurgery by the urological male surgeon assessment, and then determine the treatment plan, not directly “test tube” or “give up! “!