Targeted drugs that can be used by bowel cancer patients include bevacizumab, cetuximab, regorafenib and so on. 1. Bevacizumab: it can reduce the growth of microvessels and inhibit the progress of metastatic disease. It can be used in combination with 5-fluorouracil for the treatment of metastatic colorectal cancer, and in combination with carboplatin and paclitaxel for the treatment of unresectable advanced, metastatic or recurrent non-squamous cell non-small cell lung cancer. Side effects such as decreased appetite, bleeding, headache, high blood pressure, constipation and so on may occur in the use of the drug, and it is forbidden for those who are allergic to the ingredients of the drug. 2. Cetuximab: it can inhibit the proliferation of tumor cells, reduce the generation of tumor neovascularization and metastasis. Combined with irinotecan, it can be used to treat metastatic rectal cancer with epidermal growth factor receptor and failure of irinotecan-containing treatment. Headache, hypomagnesemia, elevated liver enzyme levels, rash and other adverse reactions can occur in the drug, and it is forbidden for those who have serious hypersensitivity reaction to cetuximab. 3. Regorafenib: it can inhibit angiogenesis of tumor tissues and control tumor metastasis. For patients with intestinal cancer, it is suitable for patients with metastatic colorectal cancer who have previously received chemotherapy based on fluorouracil, oxaliplatin and irinotecan, and those who have received or are not suitable to receive anti-vascular endothelial growth factor therapy and anti-epidermal growth factor receptor therapy (RAS wild-type). There are also targeted drugs such as furaquintinib, and more targeted drugs may be available in the future as medicine advances. Adverse reactions such as anemia, bleeding, high blood pressure, and vomiting can occur with the drug, and it is contraindicated for those who have a hypersensitivity reaction to the drug components. Regardless of which drug, patients should be used under the guidance of a doctor, standardized treatment, do not blindly use or stop the drug.