Waking up in the middle of the night every day is a sleep disorder, clinically caused by a variety of reasons, such as the patient’s excessive mental stress can cause. If the patient stays up excessively late, it may cause biological clock disorder, and the patient can have this condition, mainly relax and develop good habits, which may improve. If the patient has a mental disorder disease, it can also be caused, generally seen in patients with depression, while the patient may appear depressed mood, self-evaluation ability is reduced, not interested in anything, the patient can also appear dizziness, head swelling and peripheral weakness and other various symptoms, generally to be antidepressant treatment, commonly used drugs are tandospirone, mirtazapine, Dextran and citalopram.