As we all know, we call the ability of the auditory organs to perceive sound hearing, and the clinical evaluation of good or bad hearing to find a standard that can be standardized by a number, this is the role of the “hearing threshold”. In clinical practice, the hearing threshold of a normal hearing person of about 20 years old is generally taken as the average of the hearing threshold of each frequency as 0dB, and the decibel of the hearing loss of the patient is measured. If the patient has a hearing loss of 30 dB or more, i.e., the hearing threshold for that frequency is raised by 30 dB, he or she can be diagnosed as deaf. Noise is very strong and the top of the spectrum changes a lot, jumping up and down, etc. When noise damages the ear, it causes a rise in the hearing threshold. So, what causes can cause the hearing threshold to rise? The following is a brief introduction: 1, mainly due to a long time in a more mocking environment, noise pollution is more serious, serious damage to the ear occurred and caused. 2, infectious deafness: various acute infectious diseases, bacterial or viral infections, such as epidemic B encephalitis, mumps, purulent meningitis, measles, scarlet fever, influenza, ear herpes zoster, typhoid fever, etc. can damage the inner ear and cause sensorineural deafness of different severity. 3.Drug intoxication deafness: Mostly seen in aminoglycoside antibiotics, such as gentamicin, kanamycin, polymyxin, dihydrostreptomycin, neomycin, etc. Other drugs such as quinine, salicylic acid, cisplatin, etc. can cause sensorineural deafness, and ear drug intoxication is closely related to the susceptibility of the body. Drug-induced deafness is bilateral, mostly accompanied by tinnitus, and vestibular function can also be impaired. Long-term use of these drugs in the middle ear can also leak into the inner ear through the cochlear membrane, which should be noted.