Skin allergies are only treated with injections when they are severe, usually including intravenous glucocorticoids, vitamin C, calcium, and intramuscular antihistamines. 1. Glucocorticoids: these hormones can play an anti-allergic, anti-inflammatory and immunosuppressive role, the injection of drugs generally choose methylprednisolone, dexamethasone and prednisolone, etc., should not be used for a long time, so as not to cause osteoporosis and hormone dependence. 2. Vitamin C: It has a certain anti-allergic and detoxifying effect, which is a reducing agent that can prevent the production of oxygen free radicals, prevent oxidative damage and improve allergic symptoms. 3. Calcium: Since the use of glucocorticoids can lead to osteoporosis, calcium supplementation is usually needed to prevent the side effects of hormones, and at the same time can reduce the permeability of blood vessels, stabilize cell membranes, and reduce the release of histamine, thus alleviating the symptoms of allergy, for example, the use of calcium gluconate. 4. Antihistamines: Commonly used antihistamines are Benadryl and Promethazine, which can reduce allergic symptoms in a short time by intramuscular injection, but can cause drowsiness, fatigue, dizziness and other discomforts, and should not be used for driving and working at heights. Patients with skin allergies, it is recommended to go to the hospital in a timely manner to identify the cause and then symptomatic treatment, the drug should be used in accordance with medical advice.