Generally deeper wounds and the presence of contamination can easily bring tetanus bacilli deep into the wound to occur anaerobic bacterial infection, at which time tetanus vaccination is required. If there is trauma, patients with broken skin or wounds, especially after trauma with obvious contact with rust-like iron or clay, or during the production process, resulting in local soft tissue damage are required to be injected with tetanus. Tetanus injection is an antitoxin for tetanus, which prevents the toxin from binding to the nervous system in the body. Timely tetanus injection can prevent the occurrence of tetanus infection. If the wound is large and deep, the wound should be cleared, strictly disinfected and sutured after thorough removal of necrotic tissue, and oral antibiotics should be taken to prevent infection. Tetanus vaccination should be given as early as possible, the best time for injection is within 24 hours and should not exceed 72 hours as far as possible.