One week a glucose-lowering drug generally refers to troglitazone, which is an enzyme inhibitor, referred to as DPP-4 inhibitor, these drugs work through glucagon-like peptide-1 (GLP-1), which is a hormone secreted by the intestine, this hormone can promote insulin secretion and inhibit the secretion of glucagon-raising glucagon, and also suppress the appetite of patients, reduce the amount of food patients eat, from It can also suppress the appetite of patients and reduce the amount of food they eat, thus lowering glucose in many ways. However, after GLP-1 is secreted in the body, it is quickly degraded by specific enzymes and is unable to function. In this way, inhibitors of the enzyme have been developed to prevent the degradation of GLP-1 so that it can function. Troglitazone is a long-acting DPP-4 inhibitor, which is metabolized in the body mainly by the kidneys and metabolized very slowly, and after a week there is still about 70% inhibition of this enzyme, so only one is taken a week. Because troglitazone is mainly metabolized in the kidneys, it is contraindicated in patients with severe renal insufficiency.