There is no such thing as what medicine is good for enlarged prostate with calcified foci. Enlarged prostate with calcified foci may be caused by prostate hyperplasia, prostatitis, prostate cancer and other diseases, and the patients can be treated with drugs such as Doxazosin Hydrochloride tablets, Cefadroxil tablets, Methotrexate injection and so on. 1. Prostatic hyperplasia: Patients with prostatic hyperplasia will experience symptoms such as congestion and frequent urination, which will lead to enlargement of the prostate. Patients can follow the doctor’s instructions to use doxazosin hydrochloride tablets, terazosin hydrochloride tablets, tamsulosin hydrochloride extended-release capsules and other alpha-blockers, but also finasteride tablets, dutasteride tablets and other 5 alpha reductase inhibitors. 2. Prostatitis: Patients with prostatitis will experience symptoms of a full and enlarged prostate. Patients can use antibiotics such as cefadroxil tablets and levofloxacin hydrochloride capsules as prescribed by doctors. 3. Prostate cancer: the main symptoms of prostate cancer are difficulty in urination, swelling, etc. Patients need to undergo surgery, and after the surgery, they may need to be treated with chemotherapeutic drugs such as methotrexate injection, cyclophosphamide injection, 5-fluorouracil injection and so on as prescribed by doctors. Patients with enlarged prostate with calcified foci should seek timely medical examination and early treatment. All of the above drugs should be applied under doctor’s guidance.