The upper and lower diameter of the spleen is 198mm, the thickness is 45mm, and the inner diameter of the vein is 8mm suggesting that there is an enlarged spleen, which may be caused by blood diseases or liver diseases. 1. Blood diseases: spleen is the largest blood storage organ in human body, when patients suffer from severe anemia, it will make bone marrow hematopoietic function impaired and produce extramedullary hematopoiesis, so it will lead to enlargement of spleen, especially for children with blood diseases, the symptom of extramedullary hematopoiesis is more obvious, in addition, some malignant tumor cells will enter into the spleen along with the blood, which will also lead to the enlargement of spleen. 2. Liver disease: After suffering from liver disease, it will lead to the proliferation of reticuloendothelial cells in the liver and spleen, and excessive proliferation of reticuloendothelial cells in the spleen will lead to enlargement of spleen, especially after developing into cirrhosis with portal hypertension, which will make the symptom of enlargement of spleen more obvious. If enlarged spleen occurs, patients need to go to the hospital in time for blood tests and imaging tests to clarify the cause and then carry out appropriate treatment.