Mycoplasma urealyticum positivity is very common in clinical practice and is not serious when it first develops, but can be serious if it leads to complications if left untreated and can lead to infertility and other conditions. A positive Mycoplasma Liberibacter indicates the presence of Mycoplasma Liberibacter infection in the body, which occurs mainly through sexual transmission or contact with the patient’s clothing. The initial infection, for men, will have white transparent discharge from the urethra, soiling on the underwear, itching at the urethra and other symptoms, if not treated in time, can cause sperm deformities or even death, seriously affecting male fertility; for women, there will be vulvar itching burning sensation, increased leucorrhea, painful urination and other phenomena, if not treated in time, there will be endometritis, tubitis and other complications, leading to infertility or ectopic pregnancy. This can lead to infertility or ectopic pregnancy. If the infection occurs during pregnancy, the fetus may be delayed or even miscarried. Therefore, when an infection is detected, it should be treated with oral azithromycin, roxithromycin, etc. according to medical advice. Avoid sexual intercourse during the infection to prevent cross or recurrent infection.