Shoulder pain after drinking may be related to physiological factors, or it may be caused by shoulder joint disease, gout, cervical spondylosis and other factors. 1. Physiological factors: after drinking, especially after drunkenness, the shoulder pain after drinking may be caused by the weakening of the brain’s control over the neuromuscular ability, which leads to prolonged pressure on the limbs, or muscle injury caused by improper posture control. 2. Shoulder joint diseases: such as frozen shoulder, rotator cuff injury and other diseases, drinking alcohol may aggravate the local irritation, thus causing the symptoms of post-drinking shoulder pain to worsen. 3. Gout: Drinking alcohol can easily lead to an increase in blood uric acid, which may aggravate gout or cause gout attacks, and thus may cause shoulder pain. 4. Cervical spondylosis: If there is a history of cervical spondylosis, after drinking alcohol, especially after excessive drinking, it may aggravate the stimulation of nerve roots, which may cause shoulder pain. Shoulder pain after drinking may also be caused by other reasons. After excluding physiological factors, it is recommended to consult a doctor in a timely manner to clarify the cause of the disease and give targeted treatment.