The whitening of the sides of the nose may be caused by diseases such as pityriasis alba and vitiligo. 1. simple furuncle: the cause of the disease is unknown, may be related to microbial infections, such as Malassezia furfur, as well as heredity, malnutrition, vitamin deficiency, sun exposure and other factors. The typical manifestation of the skin lesions is a round or oval pigmented spots, preferably in the face, when the erythema subsides, it will be manifested as pale white patches, so the patient’s nose will be white on both sides. 2. Vitiligo: the cause of this disease is unknown, can be induced by overwork, skin injury, contact with chemicals and other factors, and then lead to the patient to appear on both sides of the nose white symptoms. It is recommended that the sides of the nose white timely to the hospital, perfect a series of examination, clear specific causes, the treatment of the cause.