The key to quitting alcohol lies in one’s own self-control ability. Reducing or quitting alcohol intake through self-control belongs to the healthy method of quitting alcohol. Drugs can be tried disulfiram and so on, this kind of drug application, even if a small amount of alcohol can lead to the body headache, abdominal pain, nausea, flushing, rapid heartbeat, blood pressure drop and other changes, and the drinker will be because of these discomforts, appeared to alcohol boredom or fear of emotion, to achieve the purpose of quitting alcohol. Disulfiram mainly interferes with the action of the enzyme acetaldehyde dehydrogenase in the body, so that after alcohol is broken down into acetaldehyde, it cannot be further metabolized, and acetaldehyde can act on the cardiovascular system and the nervous system, and the above symptoms occur. Although disulfiram has a relatively good effect on alcohol cessation, in the process of application, the therapeutic dose is close to the poisonous dose, and there is a possibility of life-threatening due to severe disulfiram-like reactions, which must be applied under the guidance of local doctors.