If the contents of the courier come into contact with droplets or virus-carrying material from a virus-carrying population, the contents will carry the virus, which may lead to coronavirus infection in a healthy person if not properly protected. The main modes of transmission of the new coronavirus are respiratory droplet transmission, aerosol transmission, and direct contact. Therefore, if the virus-carrying population sneezes, coughs, speaks and produces droplets carrying the virus or the droplets are mixed in the air, forming aerosols, and come into contact with the things in the courier; or the things in the courier come into direct contact with the virus-carrying substances, all of which may result in the courier carrying the virus, leading to human infections. Therefore, when coming into contact with the courier, it is necessary to disinfect it at the first time to reduce the chance of being infected, and if it comes into contact with suspicious items, it is necessary to report it in a timely manner.