Hypotension can cause cerebral infarction, and cerebral infarction occurring from hypotension is also clinically known as cerebral infarction caused by hypoperfusion, mostly seen in watershed cerebral infarction, which can occur in the anterior circulation, posterior circulation, or the middle cerebral artery perforator supply area. Patients mostly develop cerebral infarction based on vascular stenosis due to low blood pressure and insufficient blood volume. Treatment should be given to patients with anti-platelet aggregation, anticoagulation, blood circulation and blood stasis treatment, and also with volume expansion treatment, which is commonly used clinically with hydroxyethyl or vitamin C. It is also important to pay attention to the patient’s heart condition and to limit the amount of fluid if the patient has severe cardiac insufficiency. For patients who usually have hypotension, it is recommended to drink more water to avoid excessive sweating and insufficient blood volume. If atherosclerosis is present, it can be combined with statins to protect the intima if necessary after ultrasound examination.