1.The early pathophysiological changes of intestinal obstruction are enhanced intestinal peristalsis, fluid and gas accumulation in the intestinal lumen, dilatation, intestinal wall congestion and edema, blood transport disorders leading to intestinal necrosis and intestinal perforation. How to solve intestinal edema, interstitial edema and improve microcirculatory disorders so as to eliminate intestinal edema and restore intestinal function is an important link to the success of conservative treatment. Only 100 cases were treated surgically, accounting for 38.5% of cases, and most cases were cured by conservative treatment. Therefore, early use of albumin or plasma is a key step in the treatment of intestinal obstruction and should be given attention. 2. In the surgical cases, since early use of albumin or plasma did not reveal the occurrence of extensive intestinal necrosis and severe intestinal edema, extensive bowel resection was not required, thus avoiding the occurrence of short bowel syndrome. The reduction of intestinal edema and intertissue edema improves microcirculatory disorders, avoids the occurrence of extensive intestinal necrosis and severe intestinal edema, and facilitates the patient’s postoperative recovery. No serious surgical complications occurred in 100 surgical cases, achieving the purpose of exchanging the least trauma for the greatest therapeutic effect. 3.The use of drugs that inhibit the secretion of digestive juices, such as Loxac, can reduce the secretion of digestive juices, reduce the burden on the gastrointestinal tract and facilitate the recovery of intestinal functions; while the use of drugs that inhibit inflammatory reactions, such as ustekin, can block the chain of inflammatory reactions, reduce the inflammatory reactions and toxic symptoms of the patient’s whole body, and reduce the occurrence of sepsis and multi-organ failure. 4. Among 260 cases, 30 cases had a history of eating raw, cold, hot, hard, spicy and indigestible food, which is a trigger for the onset or recurrence of the disease. Therefore, it is of clinical significance to strengthen communication with patients and conduct health promotion and education to prevent and control the occurrence, development and recurrence of the disease; to return medicine to humanities and fundamentals, and to democratize and individualize medical program decisions is the treatment of the disease The correct clinical treatment path can avoid the phenomenon that the equipment becomes more and more advanced and the doctors become more and more educated, but the doctors become less and less able to see patients and the doctor-patient relationship becomes worse and worse. In conclusion, the early use of albumin or plasma in the individualized treatment of adhesive intestinal obstruction is a key step in the treatment of intestinal obstruction and should be given sufficient attention. The use of albumin and plasma should not be based on whether there is low protein in the liver function test, but must be used as early as possible because the development of intestinal obstruction and the loss of a large amount of body fluid will eventually lead to the occurrence of low protein edema.