Feeding intolerance in preterm infants refers to the fact that all factors affecting gastrointestinal dynamics can cause feeding intolerance in preterm infants. Feeding intolerance not only affects gastrointestinal feeding, but may also hinder the growth and development of preterm infants. To prevent feeding intolerance in preterm infants, it is best to use breastfeeding, which is more easily digested and absorbed, and the choice of breast milk can reduce feeding intolerance in preterm infants. In addition, a reasonable feeding program should be chosen according to the individual situation of preterm infants. Since the digestive power of preterm infants is related to the gestational cycle and individual situation, the digestive tract power of preterm infants should be properly adjusted according to individual situation so that the digestive tract power is in the best condition to avoid the occurrence of feeding intolerance.