In clinical practice, the 5p sign occurs when a patient has an acute arterial embolism. The 5p signs are pain, abnormal sensation, paresthesia, pulselessness, and pallor. In general, pain is the first symptom to appear, followed by changes in skin color and temperature, and a weakening or loss of arterial pulsation; in addition, the peripheral nerves are damaged because of the ischemic changes in the arteries. In general, arterial embolism is the blockage of the lumen of an artery by an embolus that enters the vessel, causing an obstruction of blood flow in the vessel, which results in acute ischemia. The occurrence of this disease is generally more acute, the symptoms are more obvious, the development of the disease are more rapid, if not timely treatment, the prognosis of the patient is generally bad. Therefore, generally speaking, patients with arterial embolism need to be actively given surgical treatment so that they can recover healthily.