Laparoscopic cholecystectomy also has contraindications. The following details the contraindications related to laparoscopic cholecystectomy? Absolute contraindications 1, with severe cardiopulmonary insufficiency and unable to tolerate anesthesia, pneumoperitoneum and surgery. 2, with coagulation dysfunction. 3.Acute cholecystitis with serious complications, such as gallbladder gangrene and perforation. 4.With acute severe cholangitis or acute gallstone pancreatitis. 5.Gallbladder cancer or gallbladder bulge-like lesion suspected to be gallbladder cancer. 6.Chronic atrophic cholecystitis, gallbladder volume <112,5px×37,5px, wall thickness >12,5px (measured by ultrasound). 7.Severe cirrhosis of the liver with portal hypertension. 8.Patients with middle or late pregnancy. 9, with abdominal infection, peritonitis. 10, with diaphragmatic hernia. Relative contraindications 1.Acute attack of calculous cholecystitis. 2, chronic atrophic calculous cholecystitis. 3, common bile duct stones and obstructive jaundice. 4.Mirizzi syndrome, gallbladder neck stone impaction. 5, History of previous upper abdominal surgery. 6, Morbid obesity. 7, Extra-abdominal hernia.