Scrotal itching prescriptions have no effect, scrotal itching is usually caused by bacterial infection, fungal infection, scrotal eczema and other factors, usually medication, causative factors are different, the medication is also different. 1. Bacterial infection: for bacterial infection caused by scrotal itching, usually use erythromycin ointment, mupirocin ointment and other antibacterial drugs, and in severe cases, oral cefdinir, ciprofloxacin and other drugs. 2. Fungal infection: when there is a fungal infection, it will also make the scrotum localized itching symptoms, can be used topical clotrimazole ointment, terbinafine ointment and other drugs. 3. Scrotal eczema: for scrotal eczema, you can use glycerite lotion, tacrolimus ointment and other medications to improve the symptoms of itching, and in severe cases, you should also take oral antihistamine therapy, such as cetirizine and loratadine. In the process of treatment, we must follow the doctor’s instructions, rational use of medication, do not trust any prescriptions, to avoid causing adverse reactions.