The clinical causes of hyperinsulinemia are different, so the treatment is also different. If early diabetic patients may have insulin resistance, insulin secretion in the blood is increased at this time, we can use insulin-sensitizing drugs to make the action of insulin efficient, and then its level may slowly decrease. Another thing is to lose weight and reduce insulin resistance, which also helps to reduce the insulin level in the blood. If the insulin is pathologically elevated, such as beta-cell tumor or pancreatic beta-cell tumor that causes excessive insulin secretion by beta-cells, we should treat the cause of the disease, and surgical removal of the adenoma can make significant improvement of hyperinsulinemia. Therefore, the treatment of hyperinsulinemia is closely related to its cause, and different treatment plans are needed depending on the cause.