Metformin generic name is metformin hydrochloride tablets, metformin tablets compared with gliclazide there is no absolute good or bad, depends on the patient’s sensitivity to the drug and the type of disease. Metformin tablets are usually more effective in treating obese or hyperinsulinemic diabetes, and gliclazide tablets are more effective in treating non-insulin-dependent type 2 diabetes where dietary therapy alone is insufficient to control blood sugar. Gliclazide tablets are sulfonylurea insulin secretion drugs, mainly to promote the pancreatic β-cells secretion of insulin, to reduce blood glucose effect. Patients who have been sick for many years, if the function of insulin secretion is reduced, the glucose-lowering effect of gliclazide tablets is very weak. Metformin hydrochloride tablets through increasing insulin sensitivity, at the same time inhibit the decomposition of liver glycogen in the liver, play a comprehensive effect of lowering sugar. When choosing hypoglycemic drugs for diabetic patients, they should consult with professional doctors and use drugs rationally.